Wilks also firstly described trichorrhexis nodosa ( the formation of nodes along the hair shaft ), in 1852.
2.
Other side effects in children include sparse hair growth and frontal recession, and pili torti and trichorrhexis nodosa are also sometimes present.
3.
As in previous descriptions of amino acid abnormalities in the trichorrhexis nodosa of arginosuccinicaciduria, there were increases in lysine, aspartic acid, alanine, leucine, isoleucine, and tyrosine.
4.
In some cases, trichorrhexis nodosa may be caused by an underlying disorder such as argininosuccinic aciduria, Menkes'kinky hair syndrome, Netherton's syndrome, hypothyroidism, or trichothiodystrophy.
5.
Microscopic analysis of the hair shows twisted hairs of unequal size and different shapes ( pili torti, aniso-and poikilotrichosis ), longitudinal breaks and breaks located at nodes ( trichorrhexis nodosa ).
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